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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff1b454fa035120c402771272a1f5db7249f0e4bde547d0f729d51e2374255ee' 
  AND token = '0JipJTvr8ozEa818TkN9bBFcGJ+dtBPd3h/10w0ibdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}