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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ec85f8d792092e15fc4a7019c8d52435ebdf0db9f38ab74150c55593a5a6dd' 
  AND token = 'zz+3C+kRMgdQ9BJ+hO63s4a5/avcB2S0k1XymDCyhDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}