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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e530108f2fbf0f4026b45b84e3e905cce22cf16bb13a89bed0a4af24e625a11' 
  AND token = 'HsTiAas506uq4N7l9ZBiTx+adtua6I2w2zBdNo8yYHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}