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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720c6fdb8fd075381667a612ff5ca3e52a83aada98f1202ee7f46088a5e9e095' 
  AND token = 'grJJsBcYr28tYPTyteKqUvYqBRzLtDVT13VqK4wK3LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}