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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac81476d94eeafbf4425b94cd42fd3b9d38e02db14a7577256a5ca5328b8b58' 
  AND token = 'oX3/mqx/XE3YflW9oPyyezLPaaDAE6ulAC2aHoD4WRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}