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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3217ff50d74132d44a85a55d4ea6f58164d03ec0862860af80814d4d5f881150' 
  AND token = 'ZxQzMoNr7PC+C/fcrB2ybdQk4m9VrNGJrjq3z18yrN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}