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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779a7d3ac27f8b133af3fdb47bf6c68b9182239b9926b4b9f9503ed12aeace93' 
  AND token = 'm3GKJVa+raTh0UXCyHbDxcc/IPinalZ1K8yRj3s8cNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}