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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8846cc807b9fefdc0d0a7589b0cad3bfe10c49c5161ee0f7a3a4099a0ce8181' 
  AND token = '/eEMjErczvpW5H3gSovLjnBuNg/W+R/Iy/BT4fzW+RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}