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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d18b2ca944a622c16fb7802053ed391a390022e6bb2b8ed9fde2278bd1cd4b1' 
  AND token = 'Z8YHP07cRD2azL8zwtO7D/L/x4Z6nTHn2+uoBrQ/mmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}