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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2868ada9ea1903d61c735cdc671af8b471413f7bade2f990ddd9cff24a256871' 
  AND token = 'Xly1FCWps/Zm3VX4j1DJWXgdQWU0gC/+yIjIUy8t4gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}