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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e7339b05a10ba9383541cf77ddd19cc1d412cbcb0e7625446e41a3a426c9291' 
  AND token = 'e108YCh5tx03DHHUxoadejzsoimIUQuo03tjsianf4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}