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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffb7ae50a52708ff0ef49f21742280a820dd4f3fe12568c08b8159f8dac271cf' 
  AND token = 'VAse1+D8EFvmTvIFoTf3YH5N+NOVGxXDX8DQBt2j8wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}