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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8a2fb88a228cb7f64fddcb665d980bb521fa633a781c5bae90100f34705862' 
  AND token = 'LjvN+ebaYKtXT1b2ib9pkAkVWVWlNtTcpPTi1kmprPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}