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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81045747a8c85b3640c3b471c44135493f4ad6edb0bd07a782f125dad0008ddf' 
  AND token = '2GwNhPd5HNL3IJ0U1Y8XPh8F+r997xqqZcUflRd5+Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}