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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54939a78aa08934c1c4688653fbb5a0b625b1add4a1c24204471a59cc11378c3' 
  AND token = 'E47hpT9ziM+MZ549Jn82GGsqkTKY5ZiLEyY5VG+oTVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}