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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153a37c5e7d0c4b1e7bdffa4c7b0579a12a1d0ba6d92e4e1149f966745c406a7' 
  AND token = '9T1fffe13rqqFvyndc+jKgz2hzTLt1sHMBGy5xDT2dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}