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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc3cb27f5106f64634d6a1a28848d96157a455b1b951d9e5655db536853ae22' 
  AND token = 'osXrgaaT+oTIyfhFyQ8gRV8qRyJyNAHT2V0Br0seqVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}