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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a346cc92760f86e91e65bd795be17bd80ab2381e81e043d30b63d75109983c85' 
  AND token = 'wQ1WR8ZwzLPkh6ntwbh2NNzO9kQh0LKrqoDTt+wzIGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}