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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8169cd42b4a22597e35a723811bb73fe3616a612ae6ee9f7cc2311cebf6eb345' 
  AND token = 'gnaeMgDBK1h045wj7KeRzS7NrtRcX/g7PezRzwOpbHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}