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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69522b053b5e82bd936b08d56d0a2634a663e531e6e0f44681fab92493e53b33' 
  AND token = 'XUC93Dvd5PKs8DinrTYr9Npu7BfO/WUCyRKVzto33oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}