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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '969888611a994f83f7dfcdbfe09cd21513966c1e74ecfe56c099d5f3e98f1077' 
  AND token = 'X9J3CMm6y2/+YakfzH8xvN8CyK4VFkQXR/AmMs2bZpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}