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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379576f2909020474472ca10b3e7846ec95fb6e3f650ed4825cc009aed9200e3' 
  AND token = '9tvCwpilSwM0DfkSMPEMDhNsb35EK29ZfE1Em/0FeYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}