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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad555fedb19122087802c97a9d4190917db059fca20f4ed7511cb823a207663d' 
  AND token = 'XD2ayA3iqGDNWvoUTnXXXnhEnlpeUDYgzq3uyomNEgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}