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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c19e44d24e5e0dbe014c0cdab72a649ca0bbd3e74ad514c9133aa7932c177b0' 
  AND token = 'jF0scmRKAQtcngkG9PKCXLL4zmNwLhg0lpeXAED8Pb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}