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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca48440d3d26cc10ba86c220a886b79a4f9f7ccf36dee195029e33dea4ffb5e' 
  AND token = 'tykHVGoAL7KtlehwLh7O+2g6QhiN0LVHUhqimeF7VnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}