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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f951c354b48fd376bb81f75beff9ee186b60e7df19fc703b71a955aa07b455' 
  AND token = 'IQBqOG9I8JlWMCMY1O8ua/RbY//xt8+8Na+5a3n5ZBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}