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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ffbef603971459fc491c99e994cb1c0940f34e65bdf87e98c65432855f2682' 
  AND token = '+kgdCJUWWkSh/x1oX3MZPkuHj1UX6kMoH28bY+T6XKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}