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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a6bc309da5dc3c59b53f456119566bf740f69bf5f541a1564159cbc91fd65b' 
  AND token = 'z5k4Jgkng0VkGYP7krrfoQoy792maZHMS7h4wVD14XY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}