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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7bed44f8cf43eca428b80194c12bba5bfacafdcae13ed9d13629ae43032df76' 
  AND token = 'wDYzf8cfFZ4ox4+iQEkSuLbWfCZkHKGuhJrLqxY3W8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}