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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8813b6d83cb85cfe99840f6f501462b01d7af0579a9cdd5f3eb42cfcb0ec1453' 
  AND token = 'r0wu7H1OvpLFpPxupSVLwdxJ8xGf0O+1LLtuUWkQvcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}