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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3346bc1ec6bed2733a681719d9ad78bee7ca2b939b2c7e7e13e010f2e9ca34' 
  AND token = 'QitBr4WGYv34PWhgkGVjrAS2hXXP98TBCnJje+MlGbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}