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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '894c05b8366cbd7861e6d1eaf869975ab56fd9a204c8002a48f571d8e7a22785' 
  AND token = '/UwEUI5SH3ZG5CKuf0QcrFNktWOsMiERt0FQOFSGdGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}