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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc6b325ce02f9b99a09d1642266ba151ace4e69f5a9add734ca0c80c022402c' 
  AND token = 'tuolENiVFlJwUwFhNybqaS0ONXslcnb2biV0px7+DpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}