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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc4e9c744d36ade3904edd1eb1a33e18f9c57aa341dd1c641858be6a23ff369' 
  AND token = 'MwKc+oRFKieN3wpTHspTN3sDm5+otUq0+0SvD4MJkKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}