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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7362b011932bb2ab89e950a5eff6ebd409a7570310f4636baed05f42d3aa0cc2' 
  AND token = 'rj/f5o+ONhSwJ/eEmsf5PEQFQ1hXCPHaUzIkWVIP6M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}