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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4c2bc515840280bebfebf3479ff43b5907b4cac3f580aaf4754ddeaa5d6e663' 
  AND token = 'cUaFtYlf5qdSLu4EZwvzUdi1OlVe0sMb0b6PMumt5i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}