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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397688d5a4f75aa2620e663812e2f3c76cd82304d1ecd08166945dba4c6ad206' 
  AND token = 'Ms2Am4PSq9JoLpg08B6KHXbU6Kffxnw2hEr+65QMPBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}