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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46285b342c27993be4f56d3083aa09b6ff1fb05edcee3b7e669ee870b952a253' 
  AND token = 'IJPfHkQPdW6SWiMfsMRjwv0XSNBp72CMqKGX0nJw0oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}