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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee99aa47e8c54b4e46be24926f3b3d1e42e785534ab3d9d247e7ba787e5a591c' 
  AND token = 'qUOeC85O1NBCPvE4Ez6Zpjwu7fTDrcid2+jhEWZZxOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}