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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec19052466e366ae848bd31201bf6378e3b55e0c8a5c564e9e6a98dd79edffc' 
  AND token = 'zcxpE2F8nDIqdL8XNfkc6kSfQG69vwaYeGKA36X5CyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}