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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581519085a7019eff316c91936ce10f3cd27cc189f8fc20903a6f71e65bed4b9' 
  AND token = 'BDQ2PRM41oaDxvRQQ/ErEQUocTSRrm/Kx6i55wN2vFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}