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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf246aeb4952a5957dbe97489f8b48656345f730748cbf47168a9ab414b62ab' 
  AND token = '52ecfoZXMnypb2pVA5GtAcNHa3aKsSW+xCH52MhS+Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}