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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016067b76d7cc1cf618496a537e87978fd80fbb96192fbd7f793f16eabcbc87e' 
  AND token = 'a6Ui3WHl0DarGKunfNmNrbU8bxBoy1fEc/xJT8HsP5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}