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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218aa919594955fb5ebc45c866d23e4c27f73b6c03bff9be747be8123776bbf1' 
  AND token = '2+FIlryHc4tDOGnguiXyBl5R3lkmEohV+RqA3RU5ldE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}