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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16ac9d9f3e7d01249eca16e85c480e6556de39032602f7f535ecdff6f5eb864' 
  AND token = 'Y0lLUwf9c4/G9yJBNKSmJtHCwLRrYdgASoH8epRZTCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}