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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6745e7a368213b37a2c4b7917219c60a775b5edda5c59423cea4a14ca5d0d109' 
  AND token = 'yzCx1xs2Ni9grpvfLHV+/QIA316+WBRtPLriqIbKEjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}