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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280adc30a67ce1f81fb1e9d121ead06fc1fb32ea927f31783444a23db497416d' 
  AND token = 'FX8C5q3W1PCtB65P4/6hQFY3hQDgD/8arG0uTMk/5xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}