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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c447744e3f4dd49bf414a9c886cc328f48a03b822164c606dd493315c43a86e' 
  AND token = 'pUDdvwbeJjBfiuyx7XP8VFiYbUReM2WeUoAytDEW1Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}