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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bbd1fa2fea87d11764040f6f9d2e1faa6730773ffb0b9b1a3f5991b397ddd78' 
  AND token = 'XjFevBqWv5zBg06Eh2rDpExzyrahH326+CCmNG8Rqjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}