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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a19a83f4c94816f67a284f133e838e25dadb72ea0d8375bdf66f44d5b86de9' 
  AND token = 't1Mq4W1VtqTVWv6nGWOTxspmmq6u1Z4VRKIDbmDOAZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}